When you are working ethically, keeping everyone’s interest at heart, working to make the world a better place, and not only for profit, you are already making a difference and doing business too.
Profit is a must when you are doing business; otherwise, no other goal can be achieved. Even not for profit, organizations can sustain only when they have the money. The same principle applies to business, only that it is with profit, where you are working towards benefiting a larger audience to make some difference to society.
Not having any objective is also okay, but then you look for spirituality or doing good outside of your work. And if you have combined your business and spirituality, you aim for two goals with one task.